NFL Week 16 odds: Eagles open up as 12-point Favorites over the Giants  

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Eagles nfl week 7 odds aj brown
Philadelphia Eagles wide receiver A.J. Brown runs a route against the New York Giants during the second half of an NFL football game, Sunday, Jan. 8, 2023, in Philadelphia. (AP Photo/Matt Slocum)

NFL Week 16 odds: The Philadelphia Eagles have now lost three games in a row. While the NFC East is still theirs for the taking, things are now much more difficult, and the first of two games against the Giants this season is now a must-win. Can the struggling G-Men play spoiler against their divisional foe on Christmas, or will the Eagles bounce back?

Interestingly, the Eagles have opened up as 12-point home favorites for the clash against the New York Giants.

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NFL Week 16 odds: Eagles vs Giants

Spread: Philadelphia Eagles -12 | New York Giants +12
Moneyline: Philadelphia Eagles -600 | New York Giants +440
Total: Over/Under 42.5

The Eagles open up as favorites once again after a torrid run of form. But 12 points seems like an awful lot given how putrid they have been on both offense and defense. Sure, the Giants are 5-9, but divisional games are rarely ever blowouts.

In terms of the actual rivalry,Philly leads the regular-season series with a 93-88-2 record, with the Eagles having won each of the last 4 meetings. Sprinkle in the fact that the G-Men are down to a backup QB and this doesn’t exactly bode well for Big Blue.

NFL Week 16 odds: Why you should back Philadelphia

As much as the Birds are in a state of disarray, the Giants are hardly a team who have the ability to capitalize on that. Sure, their run game is okay, but the Eagles have a top-10 run-stuffing unit and a pass rush to really put Tommy DeVito under pressure.

The Eagles need this win not only for their chances of securing the NFC East and #1 seed, but to put an end to the bleeding to what has been a dismal few weeks of play that has questions emerging from the most unsuspecting of places. The Eagles have to win on Christmas Day and if there is ever a chance for them to make a statement, it’s here.

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PHOENIX, AZ – FEBRUARY 12: Philadelphia Eagles quarterback Jalen Hurts (1) throws a pass while warming up for Super Bowl LVII between the Kansas City Chiefs and the Philadelphia Eagles on February 12, 2023, at State Farm Stadium in Glendale, AZ. (Photo by Jevone Moore/Icon Sportswire)

If you’re debating on getting in early on some week 16 action, it’s definitely not the worst idea to take advantage of the early NFL Week 16 odds. NFL lines tend to fluctuate depending on sentiment, wagers placed, and of course things like injury updates. If you’re confident that the Eagles can comfortably beat the Giants by 12 points, placing some early money on the NFL week 16 odds could prove to be profitable.

The good news is that if you are planning to place some Eagles-related wagers, you can get some amazing sign-up offers for NFL Week 16 odds-related lines. So instead of betting $20 on Philadelphia to beat the Giants, you can place that same bet with a new sportsbook and get some HUGE free bets in return! Here are some of our favorite offers:

NFL Week 16 Odds: Best Eagles vs Giants signup offers

AP Photo/Matt Slocum