49ers vs Jaguars: How to watch, betting preview & predictions ahead of Sunday’s game

49ers vs jaguars 49ers vs chiefs super bowl
San Francisco 49ers tight end George Kittle (85) celebrates after the 49ers defeated the Dallas Cowboys in an NFL football game in Santa Clara, Calif., Sunday, Oct. 8, 2023. (AP Photo/Godofredo A. Vásquez)

49ers vs Jaguars: On paper, this is a clash between two teams destined for the playoffs. The reality is anything but, however. The Niners have dropped 3 straight while the Jags have won five in a row. Can Jacksonville take advantage of a wobbling San Francisco, or will the Niners find a way back into the win column?

49ers vs Jaguars: Game info

Date: Sunday, November 12th
Time: 1:00PM ET
Location: TIAA Bank Field, Jacksonville
TV channel: FOX

49ers vs Jaguars: Betting odds

Spread: 49ers -3 | Jaguars +3
Moneyline: 49ers -170 | Jaguars +142
Total: Over/Under 44.5

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49ers vs Jaguars Betting preview

The Jags being 3-point dogs at HOME while on a 5-game win streak is wild. The Niners continue to be juiced up in terms of their pricing, but with Deebo Samuel finally returning, this might finally be the game it all comes together.

The Niners could be without Javon Hargrave which is less than ideal, but the defense has been what’s keeping them in tight games where a hobbling offense has struggled to score. Brock Purdy has been very solid for the most part, but has hit a wall lately, turning the ball over six times in his last 3 games. His 5 picks on the season have all come in that span. Given that the Jags lead the NFL in takeaways, this could be a game, at home, where Jacksonville is licking its lips.

The Jags also come into this game with the fourth-ranked run defense in the NFL, which bodes well if they plan to suffocate one of the most dynamic rushing threats in the entire league. McCaffrey hasn’t registered more than 55 yards on the ground since October 1st. If the Jags can stop the run, they have every chance of keeping Brock Purdy cold.

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INGLEWOOD, CA – SEPTEMBER 25: Jacksonville Jaguars quarterback Trevor Lawrence (16) celebrates during the NFL regular season game between the Jacksonville Jaguars and the Los Angeles Chargers on September 25, 2022, at SoFi Stadium in Inglewood, CA. (Photo by Brian Rothmuller/Icon Sportswire)
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49ers vs Jaguars Betting prediction

You’re telling me I can get the Jaguars, at home, against a struggling Niners team, AND get points? I’m in. I’ll take the Jags and the points all day.

Prediction: Jaguars +3.5

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49ers vs jaguars
San Francisco 49ers defensive end Nick Bosa (97) and defensive end Arik Armstead (91) celebrate after sacking Dallas Cowboys quarterback Dak Prescott during the first half of an NFL football game in Santa Clara, Calif., Sunday, Oct. 8, 2023. (AP Photo/Godofredo A. Vásquez)

AP Photo/Godofredo A. Vásquez