NFL Week 5 odds: The Philadelphia Eagles are 4-0 coming into this week’s clash against the resurgent Los Angeles Rams. Not many would’ve pegged the Rams to be 2-2 at this point, let alone hang tough with both the Niners and Seahawks. The Eagles could be in for a tough battle, but Vegas has them as the clear favorites.
The Eagles have opened up as 5-point road favorites for the clash against a team that has been making waves of its own in recent weeks.
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NFL Week 5 odds: Eagles vs Rams
Spread: Philadelphia Eagles -5 | Los Angeles Rams +5
Moneyline: Philadelphia Eagles -218 | Los Angeles Rams +180
Total: Over/Under 48
The Eagles open up as favorites yet again, but this is an intriguing line. Being favored 5 points on the road is a hefty statement, especially against a Rams team that has shown it has the potential to beat some of the best teams the NFC has to offer.
The Eagles are still dealing with cluster injuries in the secondary and that’s bad news considering the rise of Puka Nacua, who has stepped up and filled the void left by Cooper Kupp by amassing a stunning 501 Yards through 4 weeks! Sean Desai will have his work cut out trying to limit his production in week 5.
With that said, the fact the Eagles are still favored by 5 on the road is impressive and a clear sign that Vegas expects their trajectory to continue upward. Philly hasn’t been the most efficient passing offense, but Jalen Hurts put together a complete performance against the Commanders, putting up 319 yards in the overtime win. With a lethal rushing attack at his disposal, it’s easy to be bullish on the Eagles.
A 4-0 start for the Super Bowl runners-up is an ideal way to start the year and defeating the Rams would go a long way in bolstering their Super Bowl hopes, especially with the Cowboys advancing to 3-1 this past weekend.
As far as the NFL Week 5 odds go, it all looks sunny in Philadelphia.

If you’re debating on getting in early on some week 5 action, it’s definitely not the worst idea to take advantage of the early NFL Week 5 odds. NFL lines tend to fluctuate depending on sentiment, wagers placed, and of course things like injury updates. If you’re confident that the Eagles can comfortably beat the Rams by 5 points or more, placing some early money on the NFL week 5 odds could prove to be profitable.
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NFL Week 5 Odds: Best Eagles vs Rams signup offers
AP Photo/Matt Slocum