MLS Matchday 23 Schedule & Betting Guide: Hell is Real derby highlights the weekend

MLS, Union
Inter Miami forward Lionel Messi (10) dribbles the ball under pressure from Orlando City midfielder Martín Ojeda (11) and Orlando City defender Rafael Santos (3) during the first half of an MLS soccer match, Saturday, March 2, 2024, in Fort Lauderdale, Fla. (AP Photo/Rebecca Blackwell)

MLS Matchday 22 saw FC Cincinnati reclaim the top spot in the Eastern Conference, and San Diego FC held on to their top spot in the Western Conference even after a loss to the Houston Dynamo.

On Wednesday night, there were two MLS league games. Inter Miami defeated the New England Revolution, and LAFC defeated the Colorado Rapids.

The U.S. Open Cup and Canadian Championship quarterfinals also took place. In the U.S. Open Cup, Nashville SC beat D.C. United, 5-3. The Vancouver Whitecaps beat Valour FC, 2-1, in the Canadian Championship quarterfinals to advance, and CF Montreal drew with Forge FC, 2-2, and were eliminated on aggregate.

The Philadelphia Union’s matchup against the New York Red Bulls in the U.S. Open Cup was postponed due to inclement weather at Subaru Park. Don’t worry, though; both clubs will face each other on Saturday night anyway in league play.

MLS Matchday 23 looks to be an exciting weekend of action, mostly highlighted by the ‘Hell is Real derby’ in Ohio.

MLS
Jun 25, 2025; Vancouver, British Columbia, CAN; Vancouver Whitecaps defender Tate Johnson (28) goes down between San Diego FC forward Milan Iloski (32) and defender Oscar Verhoeven (33) during the first half at BC Place. Mandatory Credit: Anne-Marie Sorvin-Imagn Images

MLS Matchday 23 Schedule and Betting Guide

*All bets courtesy of Fanduel Sportsbook

MLS’s Saturday Schedule

Orlando City vs. CF Montreal – 7:30 pm – Inter&Co Stadium
Odds: Home -310, Draw +380, Away +650

Toronto FC vs. Atlanta United – 7:30 pm – BMO Field
Odds: Home +140, Draw +240, Away +180

Charlotte FC vs. NYCFC – 7:30 pm – Bank of America Stadium
Odds: Home +105, Draw +270, Away +230

Philadelphia Union vs. New York Red Bulls – 7:30 pm – Subaru Park
Odds: Home -120, Draw +260, Away +310

Inter Miami vs. Nashville SC – 7:30 pm – Chase Stadium
Odds: Home -120, Draw +290, Away +250

FC Cincinnati vs. Columbus Crew – 7:30 pm – TQL Stadium
Odds: Home +115, Draw +270, Away +195

Minnesota United vs. San Jose Earthquakes – 8:30 pm – Allianz Field
Odds: Home -120, Draw +290, Away +270

Chicago Fire vs. San Diego FC – 8:30 pm – Soldier Field
Odds: Home +165, Draw +260, Away +145

Sporting Kansas City vs. Seattle Sounders – 8:30 pm – Children’s Mercy Park
Odds: Home +200, Draw +270, Away +115

Austin FC vs. New England Revolution – 8:30 pm – Q2 Stadium
Odds: Home -120, Draw +250, Away +290

Real Salt Lake vs. Houston Dynamo – 9:30 pm – America First Field
Odds: Home +100, Draw +250, Away +250

Colorado Rapids vs. Vancouver Whitecaps – 9:30 pm – DICK’S Sporting Goods Park
Odds: Home +160, Away +240, Draw +160

LA Galaxy vs. D.C. United – 10:30 pm – Dignity Health Sports Park
Odds: Home -190, Draw +330, Away +430

LAFC vs. FC Dallas – 10:30 pm – BMO Stadium
Odds: Home -270, Draw +410, Away +600

MLS’s Sunday Schedule

St. Louis City vs. Portland Timbers – 7:00 pm – Energizer Park
Odds: Home +110, Draw +270, Away +210

MLS
Mar 1, 2025; Harrison, New Jersey, USA; Nashville SC goalkeeper Andy Najar (31) kicks the ball against the New York Red Bulls during the second half at Sports Illustrated Stadium. Mandatory Credit: Vincent Carchietta-Imagn Images

MLS Standings

MLS’s Eastern Conference

FC Cincinnati – 42 pts
Nashville SC – 41 pts
Philadelphia Union – 40 pts
Columbus Crew – 38 pts
Inter Miami – 35 pts
Orlando City – 34 pts
NYCFC – 31 pts
New York Red Bulls – 30 pts
Chicago Fire – 28 pts
Charlotte FC – 26 pts
New England Revolution – 24 pts
D.C. United – 19 pts
Atlanta United – 18 pts
Toronto FC – 17 pts
CF Montreal – 14 pts

MLS’s Western Conference

San Diego FC – 39 pts
Vancouver Whitecaps – 38 pts
Minnesota United – 37 pts
Portland Timbers – 33 pts
Seattle Sounders – 30 pts
LAFC – 29 pts
San Jose Earthquakes – 28 pts
Houston Dynamo – 26 pts
Colorado Rapids – 26 pts
Austin FC – 26 pts
Sporting Kansas City – 23 pts
Real Salt Lake – 22 pts
FC Dallas – 21 pts
St. Louis City – 15 pts
LA Galaxy – 12 pts

MLS
May 10, 2025; Harrison, New Jersey, USA; New York Red Bulls defender Kyle Duncan (6) battle for the ball against LA Galaxy defender Zanka (5) during the first half at Sports Illustrated Stadium. Mandatory Credit: Vincent Carchietta-Imagn Images TPX IMAGES OF THE DAY

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Featured Image Credit: AP Photo/Rebecca Blackwell